Career
Lord Stafford fought under his father-in-law in support of the House of Lancaster during the First Battle of Street Albans. Stafford married Lady Margaret Beaufort, daughter of Edmund Beaufort, 2nd Duke of Somerset and Lady Eleanor Beauchamp. By her mother, Lady Margaret was a niece of Anne de Beauchamp, 16th Countess of Warwick and as such, a cousin to Isabel, Duchess of Clarence and queen consort Anne Neville.
Lord and Lady Stafford had a single son, Henry (4 September 1455 – 2 November 1483).