Career
He worked as medical doctor for the Department of Public Health in Aleppo. Khalidi was mayor of Jerusalem from 1934 to 1937, succeeding Raghib al-Nashashibi. On 23 June 1935 he founded the Reform Party and on the formation of the Arab Higher Committee on 25 April 1937 was the party's representative on the AHC. The Reform Party was dissolved and Khalidi was one of the leaders arrested.
He was removed as mayor of Jerusalem and deported to the Seychelles, together with four other Arab nationalist political leaders. He was released in December 1938 to enable him to take part in the London Conference in February 1939, and was among those rejecting the British Government's White Paper of 1939. He returned to Palestine in 1943 and joined the reformed Arab Higher Committee in 1945, becoming its secretary in 1946.
He published a book of his memoirs in the same year, while exiled in Beirut. He prospered under Jordanian rule, he was custodian and supervisor of the Haram al-Sharif in 1951, became a cabinet minister (for Foreign Affairs) and briefly prime minister in 1957. In 1958, he wrote a book in English entitled Arab Exodus, though it has never been published.
He died on 26 December 1966.