Career
As such she was styled Princess of Beira. She was the presumptive heir to the throne of Portugal between 1668 and 1689, the year her half-brother John was born. She was born at the Ribeira Palace in 1669.
Marriage prospects
As such the match was dropped.
Other proposed candidates included Gian Gastone de" Medici (future Grand Duke of Tuscany), le Grand Dauphin son of Louis XIV, Charles II of Spain, the Duke of Parma as well as a Count Palatine of Neuburg. Nothing came of these plans.
Foreign this she was nicknamed Sempre-noiva, "Always-engaged". Death and burial
She died of smallpox in 1690 when she was just 21 years old.
Isabel Luísa is buried at the Monastery of São Vicente de Fora in Lisbon after being moved from the Convent of the Francesinhas.