Career
He is most well known for directing Jason X and Skinwalkers. With The Fly, Isaac also started a regular association with David Cronenberg, who brought Isaac on again for Naked Lunch and eXistenZ. Isaac"s work for Sean South. Cunningham on House II: The Second Story and DeepStar Six led to Isaac"s first turn at helming a feature when he served as a replacement director on The Horror Show (released in some markets as "House III"). lieutenant would be more than 10 years later when Cunningham would subsequently hire Isaac to direct the 10th installment of the Friday the 13th franchise - Jason X.
Isaac later directed Skinwalkers, an action movie with a plot based on werewolves, and the monster movie Pig Hunt.
He died of multiple myeloma on May 6, 2012.
