Background
He was born in Pisa, the son of Iacopo I Appiani, and followed his brother Gherardo to Piombino when he became lord of the Tuscan city.
He was born in Pisa, the son of Iacopo I Appiani, and followed his brother Gherardo to Piombino when he became lord of the Tuscan city.
In reply Emanuele married in 1445 to Colia de" Giudici, illegitimate daughter of King Alfonso V of Naples, who marched to Piombino with an army. Orsini died of plague, followed soon afterwards by Caterina, and Emanuele could enter Piombino in 1452 after being elected lord by the city"s Elders.