Career
Born in Sonderburg, she was the second of the four children born from the marriage of John Christian, Duke of Schleswig-Holstein-Sonderburg and Countess Anna of Oldenburg-Delmenhorst. In Weimar on 14 August 1656, Christine Elisabeth married John Ernest, Hereditary Prince of Saxe-Weimar. They had five children:
Anna Dorothea (Weimar, 12 November 1657 - Quedlinburg, 23 June 1704), Abbess of Quedlinburg (1685).
Wilhelmine Christine (Weimar, 26 January 1658 - Sondershausen, 30 June 1712), married on 25 September 1684 to Christian William I, Count of Schwarzburg-Sondershausen.
Eleonore Sophie (Weimar, 22 March 1660 - Lauchstädt, 4 February 1687), married on 9 July 1684 to Philipp, Duke of Saxe-Merseburg-Lauchstädt. William Ernest, Duke of Saxe-Weimar (Weimar, 19 October 1662 - Weimar, 26 August 1728).
John Ernest III, Duke of Saxe-Weimar (Weimar, 22 June 1664 - Weimar, 10 May 1707). After the death of her father-in-law (1662), she became Duchess of Saxe-Weimar.
She died in Weimar aged 40.
She was buried in the Fürstengruft, Weimar.