Career
Her father unsuccessfully proposed her as heir to the throne in early 1347, in the absence of a male heir. On 8 February 1351 at Perpignan, was performed the betrothal between Constance and Louis I of Anjou, son of King John II of France. However, the marriage never took place.
On 11 April 1361 at Catania, Constance married King Frederick III of Sicily.
In 1363 Constance died in Catania, Sicily, either from the plague, or following childbirth complications. She is buried in the Cathedral of Catania.