She was granted the titles Baroness of Zinnenburg, Margravine of Burgau, Landgravine of Mellenburg and Countess of Oberhohenberg and Niederhohenberg. Her family, the Welsers of Augsburg, were merchants and financiers of European significance and great wealth. Already at a young age, she was renowned for both her beauty and her learning.
She died at Schloss Ambras, Innsbruck in Tyrol.
She was the mother of Margrave Andrew of Burgau, who became a Cardinal, and Charles, Margrave of Burgau, who became a noted General.