He graduated from Ramakrishna Mission Vidyamandira (a residential college) at Belur before taking a Masters in English from The University of Calcutta.He did his Doctor of Philosophy from Jadavpur University.
Mukhopadhyay started his career as Regional Secretary,East India, of Sahitya Akademi. He is now working as the Director of the Publishing Department, Visva-Bharati. He is associated with a number of Bengali Little Magazines.
Presently he is a member of the Executive Board of the Sahitya Akademi.