He turned professional in 1995, after winning the French Amateur Championship. Jacquelin began his professional career on the Challenge Tour. In 1997 he claimed two wins on his way to fourth on the season ending money list, which was sufficient to grant him full playing privileges on the European Tour for the following season.
Jacquelin had to wait for his first title at the top level, eventually winning on his 238th European Tour start at the 2005 Open de Madrid.
His second victory came in 2007 at the Bayerische Motoren Werke Asian Open. During part of 2007 and 2008 Jacquelin was the highest ranked French golfer on the Official World Golf Ranking.
The event had to be concluded on a Monday after bad weather had curtailed Sunday"s play. In April 2013, Jacquelin claimed his fourth European Tour title in a record equaling sudden-death playoff at the Open de España.
After shooting a one-under-par 71 in the final round, Jacquelin was in a three-way tie at the top alongside Felipe Aguilar and Maximilian Kieffer.
All three parred the first two playoff holes, before Aguilar was eliminated on the third when he could only make par. Jacquelin and Kieffer played the 18th hole five more times with scores of par made by both. The playoff, lasting over two hours, was the joint longest (nine holes) in the history of the European Tour alongside the 1989 KLM Dutch Open.
1995 French Amateur Championship European Tour wins (4) Challenge Tour wins (2) Other wins (1) DNP = Did not play CUT = missed the half-way cut "T" = tied Yellow background for top-10.
Summary Alfred Dunhill Cup (representing France): 2000 World Cup (representing France): 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2011 Seve Trophy (representing Continental Europe): 2002, 2003, 2007, 2011.