Kane attended Ithaca High School and Cornell University, where he established himself as a sprinter.
As a senior at Cornell, he was elected to the Sphinx Head Society. In 1936, Kane was the manager of the United States. Olympic track team He became Acting Director of Cornell Athletics from 1941 to 1944 and then served as the Director of Cornell Athletics from 1944 to 1971, succeeding James Lynah.
Kane served as the Dean of Physical Education and Athletics before from 1971 to 1976.
Kane was also a leader of national and international influence who capped three decades in the Olympic movement as president of the United States Olympic Committee from 1977 to 1980. He founded the National Sports Festival, later renamed the United States. Olympic Festival.
Kane was inducted into the United States. Olympic Hall of Fame in 1986. Kane is also the author of Good Sports: A History of Cornell Athletics.