Leake was the eldest son of Robert Leake of Manchester and Mary Lockett of Salford, Lancashire.
After a private education he became head of Lockett, Leake and Company, engravers to calico printers. Leake became involved in Liberal politics in Manchester in the 1860s, and was over time president of the Manchester Liberal Association, the Manchester Reform Club and the Liberal Association of Salford. However, he declined to be a parliamentary candidate until the 1880 general election.
The Redistribution of Seats Acting 1885 divided the South East Lancashire seat into eight single-member constituencies.
Leake was elected as the first Member of Parliament for the new South East Lancashire, Radcliffe cum Farnworth Division. He was reelected in 1886 and 1892.
Prior to the 1895 general election, Leake announced his decision to resign. Leake made his residence at "The Dales", Whitefield, near Manchester.
23rd United Kingdom Parliament. 24th United Kingdom Parliament. 25th United Kingdom Parliament.