Career
At club level O'Keeffe enjoyed a lengthy career, playing with Mooncoin in Kilkenny, St. Peter's in Meath and Borris-in-Ossory in Laois. In retirement from playing O'Keeffe served as a high-ranking referee and was heavily involved in the administration of the GAA. He was chairman of the Leinster Council, before serving as President of the GAA from 1935 to 1938.