Wilkinson was first elected to public office as a Calgary city councillor in 1935. Wilkinson then ran as a Social Cr candidate in the Calgary provincial electoral district in the 1944 Alberta general election. She was elected to the district taking the third seat of five and officially elected on the 15th count.
Wilkinson ran for a second term in office in the 1948 Alberta general election.
The 195 Alberta general election saw Wilkinson lose significant support. She barely hung onto a seat winning the fifth out of six seat in the district.
Calgary electoral district was abolished in favor of single member riding"son Wilkinson ran in the new electoral district of Calgary North.