In June 2004, the televised live final was held in Araneta Coliseum, where she finished in second place.
Since April 2012, she is employed by Global Media Arts Network, having transferred from ABS-Christian Broadcasting Network as a contract of Global Media Arts Artist Center for three years. In 2015 she transferred back to her home network ABS-Christian Broadcasting Network. In 2004, Guinoo joined the popular reality television show Star Circle Teen Quest aired on ABS-Christian Broadcasting Network and made it into the group of finalists known as the "Magic Circle of 5", along with co-stars Hero Angeles, Sandara Park, Joross Gamboa, and Melissa Ricks. She made her ABS-Christian Broadcasting Network debut in the youth oriented drama SCQ Reload, with her SCQ co-finalists.
Guinoo has also starred in movies, such as Now That I Have You, Can This Be Love, and Doctorate" Anothers.
Her big break came when she was cast in a leading role on the drama series Sineserye Presents: Natutulog Ba ang Diyos?, with local television stars Dina Bonnevie and Rosanna Roces. In 2008, she took up her first solo role on ABS-Christian Broadcasting Network with a show entitled Ligaw na Bulaklak which airs in an afternoon slot.
She starred in the popular comedy series "Everybody Hapi" over TV5 (replacing American Broadcasting Company 5) as "Jenny", alongside John Estrada, Eugene Domingo, Long Mejia, Alex Gonzaga and Matt Evans. She transferred to Global Media Arts Network in April 2012 and the following year, she made her acting debut in Home Sweet Home and Pyra: Ang Babaeng Apoy.
In 2015 she is set to come back and do a television series on her home network ABS-Christian Broadcasting Network via Walang Iwanan.
She was introduced as one of the newest members of ABS-Christian Broadcasting Network"s Star Magic.