He attended schools in Kappel, Basel, Strasbourg, Lausanne and Marburg and studied mathematics and poetry in addition to theology.
Heinrich Bullinger assumed responsibility for Gwalther"s upbringing. He learned French and Italian in Lausanne. Landgrave Philip of Hesse brought the gifted student along to the Regensburg Colloquy in 1541.
When he returned to Zurich, he received the pastorate of Saint Peter"s Church to replace Leo Judicial
He was an inspiring and popular preacher. His sermons and biblical commentaries have been frequently printed and widely read.
As Zwingli’s son-in-law, he sought to preserve the great reformer"s heritage and remained true to his theological orientation. Gwalther"s Latin translations of Zwingli"s works helped disseminate his thought in the Romance language world.
Foreign Bullinger, he was a valuable collaborator in the management of the Zurich church and in assisting with his widely dispersed correspondence network.
Outside of historical narratives, he produced numerous translations, and composed Latin poems and spiritual songs. Following Bullinger’s wish, Gwalther was elected in 1575 as his successor as Antistes at the Grossmünster. He held this difficult office until 1585, when his declining mental state forced him from the post.
He had contacts with English Calvinists through John Parkhurst, in exile in Zurich in the 1550s.
Gwalther was in regular communication with English bishops.