Background
Rup was born on September 27, 1953, in Hamirpur, India.
Rup was born on September 27, 1953, in Hamirpur, India.
Bachelor of Science, Dayanand Anglo-Vedic College, Jalandar, India, 1973. Master of Science, K.U.K., Kurukshetra, India, 1975. Doctor of Philosophy, Delhi University, 1980.
1. Professor at Department of Zoology, University of Delhi (April 13, 2000 -September 30, 2018)
2. Reader at University of Delhi (April 13, 1992 -March 2000)
3. Lecturer at Sri Venkateshwara College, University of Delhi (July 23, 1979 - April 12, 1992)
Visiting Scientist at the Department of Genetics, University of Kaiserslautern, Kaiserslautern, Germany (May - June, 2004).
Visiting Scientist at the Department of Genetics, University of Kaiserslautern, Kaiserslautern, Germany (June - July, 2002).
Visiting Scientist at the Department of Genetics, University of Kaiserslautern, Kaiserslautern,Germany (November - December, 2001).
Visiting Scientist at the Department of Biochemistry, University of Cambridge, Cambridge United Kingdom (9th February - 1st May, 1998).
Total Publications: 203
TOP 20 RESEARCH PUBLICATION
1. Maji, A., Misra, R., Dhakan, D. B., Gupta, V., Mahato, N. K., Saxena, R., Mittal, P., Thukral, N., Sharma, E., Singh, A., Virmani, R., Gaur, M., Singh, H., Hasija, Y., Arora, G., Agrawal, A., Chaudhry, A., Khurana, J. P., Sharma, V. K., Lal, R. and Singh, Y. 2018. Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers. Environ. Microbiol. 20: 402-419.
2. Mahato, N., Gupta, V., Singh, P., Kumari, R., Verma, H., Tripathi, C., Rani, P., Sharma, A., Singhvi, N., Sood, U., Hira, P., Kohli, P., Nayyar, N., Puri, A., Bajaj, A., Kumar, R., Negi, V., Talwar, C., Khurana, H., Nagar, S., Sharma, M., Mishra, H., Singh, A.K., Dhingra, G., Negi R.K., Shakarad, M., Singh, Y., Lal, R. 2017. Microbial Taxonomy in the era of OMICS: application of DNA sequences, computational tools, and techniques. Antonie van Leeuwenhoek 110: 1357-1371
3. Verma, H., Bajaj, A., Kumar, R., Kaur, J., Anand, S., Nayyar, N., Puri, A., Singh, Y., Khurana, J.P., Lal, R. 2017. Genome Organization of Sphingobiumindicum B90A: An Archetypal Hexachlorocyclohexane (HCH) Degrading Genotype. Genome Biol. Evol. 9: 2191-2197.
4. Tripathi, C., Mishra, H., Khurana, H., Dwivedi, V., Kamra, K., Negi, R. K., Lal, R. 2017. Complete genome analysis of Thermus parvatiensis and comparative genomics of Thermus spp. provide insights into genetic variability and evolution of natural competence as strategic survival attributes. Frontiers Microbiol. 8: 1410
5. Kumar, R., Verma, H., Haider, S., Bajaj, A., Sood, U., Ponnusamy, K., Nagar, S., Shakarad, M., Negi, R. K., Singh, Y., Khurana, J. P., Gilbert, J.A., Lal, R. 2017. Comparative Genomic Analysis Reveals Habitat-Specific Genes and Regulatory Hubs within the Genus Novosphingobium. systems 2: e00020-17.
6. Patel, V., Sharma, A., Lal, R., Al-Dhabi, N. A., Madamwar, D. 2016. Response and resilience of soil microbial communities inhabiting in edible oil stress/contamination from industrial estates. BMC Microbiol. 16: 50
7. Gupta, V., Haider, S., Sood, U., Gilbert, J. A., Ramjee, M., Forbes, K., Singh, Y., Lopes, B.S., Lal, R. 2016. Comparative genomic analysis of novel Acinetobacter symbionts: A combined systems biology and genomics approach. Sci. Rep. 6: 29043.
8. Garg, N., Lata, P., Jit, S., Sangwan, N., Singh, A. K., Dwivedi, V., Niharika, N., Kaur, J., Saxena, A., Dua, A., Nayyar, N., Kohli, P., Gueke, B., Kunz, P., Rentcsch, D., Holliger, C., Kohler, H. P., Lal, R. 2016. Laboratory and field scale bioremediation of hexachlorocyclohexane (HCH) contaminated soils by means of bioaugmentation and biostimulation. Biodegradation. 27: 179-193.
9. Sharma, A., Gilbert, J. A., Lal, R. 2016. (Meta)genomic insights into the pathogenome of Cellulosimicrobium cellulans. Sci. Rep. 6: 25527.
10. Sharma, A., Sangwan, N., Negi, V., Kohli, P., Khurana J. P., Rao, D. L. N., Lal, R. 2015. Pan-genome dynamics of Pseudomonas gene complements enriched across hexachlorocyclohexane dumpsite. BMC Genomics 16: 313.
11. Sangwan, N., Lambert, C., Sharma, A., Gupta, V., Khurana, P., Khurana, J. P., Gilbert, J. A., Sockett, R. E., Lal, R. 2015. Arsenic-rich Himalayan hot spring metagenomics reveals genetically novel predator-prey genotypes. Environ. Microbiol. Rep. 7: 812-823
12. Verma, H., Kumar, R., Oldach, P., Sangwan, N., Khurana, J. P., Gilbert, J. A., Lal, R. 2014. Comparative genomic analysis of nine Sphingobium strains: Insights into their evolution and hexachlorocyclohexane (HCH) degradation pathway. BMC Genomics 15: 1014.
13. Sangwan, N., Verma, H., Kumar, R., Negi, V., Lax, S., Khurana, P., Khurana, J. P., Gilbert, J. A., Lal, R. 2014. Reconstructing an ancestral genotype of two hexachlorocyclohexane degrading Sphingobium species using metagenomic sequence data. ISME J. 8: 398-408
14. Nigam, A., Almabruk, K. H., Saxena, A., Jongtae, Y., Mukherjee, U., Kaur, H., Kohli, P., Kumari, R., Singh, P., Zakharov, L. N., Singh, Y., Mahmud, T., Lal, R. 2014. Modification of rifamycin polyketide backbone leads to improved drug activity against rifampicin-resistant Mycobacterium tuberculosis. J. Biol. Chem. 289: 21142-21152.
15. Verma, M., Lal, D., Saxena, A., Anand, S., Kaur, J., Kaur, J., Lal, R. 2013. Understanding alternative fluxes/effluxes through comparative metabolic pathway analysis of phylum actinobacteria using a simplified approach. Gene 531: 306-317.
16. Gupta, S. K., Lal, D., Lata, P., Sangwan, N., Garg, N., Holliger, C., Lal, R. 2013. Changes in the bacterial community and lin genes diversity during biostimulation of indigenous bacterial community of hexachlorocyclohexane (HCH) dumpsite soil. Microbiol. 82: 234-240.
17. Geueke, B., Garg, N., Ghosh, S., Fleischmann T., Holliger, C., Lal, R., Kohler H. P-E. 2012. Metabolomics of HCH-transformation: Lina to LinB ratio determines the metabolic fate of HCH isomers. Environ. Microbiol. 15: 1040-1049.
18. Sharma P., Raina, V., Kumari, R., Malhotra, S., Dogra, C., Kumari, H., Kohler, H. P., Buser, H. R., Holliger, C., Lal, R. 2006. Haloalkane Dehalogenase LinB is responsible for beta- and delta hexachlorocyclohexane transformation in Sphingobium indicium B90A. Appl. Environ. Microbiol. 72: 5720-5727.
19. Sure, M., Hauser, A., Poiger, T., Buser, H. R., Müller, M. D., Dogra, C., Raina, V., Holliger, C., van der Meer, J. R., Lal, R., Kohler, H. P. 2005. Enantioselective transformation of alpha-hexachlorocyclohexane by the dehydrochlorinases LinA1 and LinA2 from the soil bacterium Sphingomonas paucimobilis B90A. Appl. Environ. Microbiol. 71: 8514-8518
20. Lal, R., Lal, S., Grund, E., Eichenlaub, R. 1991. Construction of a hybrid plasmid capable of replication in Amycolatopsis mediterranei. Appl. Environ. Microbiol. 57: 665-671.
Elected Fellow of Academies
1. Fellow of Indian National Science Academy (FNA)
2. Fellow of National Academy of Science (FNASc)
3. Fellow of National Academy of Agricultural Sciences (FNAAS)
4. Fellow of Academy of Microbiological Sciences (FAMSc).
Fellowships Awarded
1. Awarded Endeavour Executive Fellowship by Government of Australia. To work at Murdoch University, Perth, Australia (November 2018- January 2019).
2. Awarded short-term Alexander von Humboldt Research Fellowship. Worked at Helmholtz Centre for Environmental Research, UFZ, Leipzig, Germany (June - July, 2017 and May – July, 2018).
3. Awarded short-term Alexander von Humboldt Research Fellowship. Worked at the University of Freiburg, Institute of Pharmaceutical Sciences, Pharmaceutical Biology and Biotechnology, Germany (July – August, 2013).
4. Awarded Indo-US professorship for the year 2008-09 by American Society for Microbiology to conduct research on “Genetic Manipulations of Amycolatopsis mediterranei S699 for the production of rifamycin analogs” at College of Pharmacy, Oregon State University, Corvallis (May – June, 2009).
5. Awarded short-term Alexander von Humboldt Research Fellowship. Worked on the project entitled, “Annotation of genome of Amycolatopsis mediterranei S699” at the University of Bielefeld, Gentechnologie/Mikrobiologie, Germany (July, 2008).
6. Awarded short-term Alexander von Humboldt Research Fellowship. Worked on the project entitled “Genome sequence and analysis and annotations” at the University of Bielefeld, Gentechnologie/Mikrobiologie, Germany (June - July, 2004).
7. Awarded DBT short-term Overseas Associateship to work with Prof. John Cullum at the Department of Genetics, University of Kaiserslautern, Germany (May - October, 2000).
8. Awarded short-term Alexander von Humboldt Research Fellowship. Worked on the project, “Cloning of Rifamycin bio¬synthetic genes in Amycolatopsis mediterranei” at the University of Bielefeld, Gentechnologie/Mikrobiologie, Germany (May - July, 1995).
9. Awarded Alexander von Humboldt Research Fellowship. Worked at the University of Bielefeld, Gentech¬nologie/Mikrobiologie, Germany (July, 1988 - August, 1990).
