Samson Tam graduated from Chinese University of Hong Kong with a Bachelor of Science degree.
Samson Tam is the chairman and one of the founders of Group Sense (International) Limited, the manufacturer of "Instant-Dict" Chinese-English electronic dictionary. He is also the president of Kitchee SC.
Samson Tam won the seat of functional constituency (information technology) in the Legislative Council of Hong Kong election in the year 2008. In the run-up to the 23 June 2010 Legco vote on the Hong Kong government's 2009 reform package, he offered his support if it included the Democratic Party's compromise proposal to have the five new district council functional constituency seats returned by popular election. In the year 2012, he lost his seat in the Legislative Council of Hong Kong to Charles Mok, by 765 votes.