Career
Born in Franklin County, Pennsylvania, Samuel Crothers was raised in Kentucky from 1787 until 1804. In 1809, following his seminary training, Crothers was licensed to preach. This post lasted until 1813, when he devoted his time fully to the Hop Run Church.
Crothers is notable for having spent much of his lifetime writing and speaking against those who had made a biblical case for slavery, especially in his articles published in the Quarterly Anti-slavery Magazine.
Crothers, a well-respected theologian and debater, debated the issue with theological giants of the era including Charles Hodge.