Career
He held the ranks of colonel (pułkownik) in the Royal Army, chorąży (ensign) of Orsza and Grand Lithuanian Guardian. During The Deluge - Swedish invasion of Poland in 1650s - he led a konfederacja, military rebellion against hetman Janusz Radziwiłł who betrayed the Commonwealth and allied himself with the Swedes. Later he joined the Tyszowce Confederation.
He was one of the Polish commanders in the Russo-Polish War (1654–1667), he fought in the battle of Połonka.
After the war he supported the Polish kings, opposing among others the Lubomirski"s Rokosz. Samuel Kmicic may have served as the inspiration for the fictional Andrzej Kmicic, hero of Henryk Sienkiewicz"s novel Potop.