Career
Ponzinibbio began training kickboxing when he was 13 years old growing up in Argentina. He began training mixed martial arts and turned professional in 2008 competing in regional promotions in South America
The Ultimate Fighter: Brazil
Over the course of the show, Santos defeated Marcio Santos by TKO and Cleiton Duarte by unanimous decision to reach the semifinals. In the semifinals, he defeated Leonardo Santos by unanimous decision.
However, Ponzinibbio broke his hand during this semifinal fight and was replaced by Santos in the finals against William Macário.
The semifinal-round fight with Santos, however, was picked as the Fight of the Season, and his finish of Marcio Santos earned Knockout of the Season which earned Ponzinibbio $50,000 bonuses. Ultimate Fighting Championship
Ponzinibbio faced Ryan LaFlare on November 9, 2013 at UFC Fight Night 32.
Ponzinibbio was briefly linked to a bout with Jordan Mein on April 19, 2014 at UFC on Fox 11. However, Ponzinibbio was scratched from the bout and replaced by Hernani Perpetuo.
Ponzinibbio was expected to face Ildemar Alcântara on July 5, 2014 at UFC 175.
However, Ponzinibbio was forced out of the bout with a knee injury. He was replaced by Kenny Robertson. Ponzinibbio was expected to face Sérgio Moraes on September 13, 2014 at UFC Fight Night 51.
However, Moraes pulled out of the bout citing a lingering knee injury and was replaced by Wendell Oliveira.
Ponzinibbio defeated Oliveira by TKO in the first round. Ponzinibbio faced Sean Strickland on February 22, 2015 at UFC Fight Night 61.
Ponzinibbio faced Lorenz Larkin on June 27, 2015 at UFC Fight Night 70. He lost the fight via TKO in the second round and earned a Fight of the Night bonus.
Ponzinibbio faced Andreas Ståhl on December 10, 2015 at UFC Fight Night 80.
Ponzinibbio is expected to face Court McGee on April 16, 2016 at UFC on Fox 19. Ultimate Fighting Championship
Fight of the Night (One time) versus Lorenz Larkin.