Career
Pettis went to Pius XI High School. He is the younger brother of former UFC Lightweight Champion Anthony Pettis. Early career
Pettis turned pro on September 10, 2011 against Kyle Vivian at Canadian Fighting Championship 7.
On January 7, 2012 Sergio took on Mike Lindquist at Madtown Throwdown 26.
Pettis fought Tom McKenna at LFC 53. Pettis then took on Tony Zelinski at NAFC: Unleashed.
Pettis took on Chris Haney at NAFC: Colosseum. In his next fight, Pettis defeated Jimmy Jones via unanimous decision at RFA 4-Griffin vs Escudero.
Pettis was originally set to face Matt Manzanares at Resurrection Fighting Alliance 7, but Manzanares was forced out of the bout due to injury.
RFA could not find another opponent for Sergio, therefore the bout was scrapped. Pettis is now set to face Josh Robinson at NAFC: Battleground. Pettis improved his record to an unblemished 7-0 with the unanimous decision victory.
Resurrection Fighting Alliance announced that Pettis will take on UFC vet Jeff Curran for the inaugural RFA Flyweight Championship at RFA 8 on June 21, 2013 inside the historic The Rave/Eagles Club Milwaukee, Wisconsin
Curran was forced out of the bout due to personal reasons, RFA President Editor Soares reported that Dillard Pegg will take his place and fight Pettis for the flyweight title. Pettis faced James Porter for the NAFC Bantamweight Championship, at NAFC: Battle in the Ballroom on September 28, 2013.
Ultimate Fighting Championship
Pettis was expected to make his promotional debut against Vaughan Lee in a bantamweight bout on November 16, 2013 at UFC 167. A week before the fight Lee was forced out of the bout due to injury and was replaced by Will Campuzano.
In his second UFC bout, Pettis faced Alex Caceres at UFC on Fox 10 on January 25, 2014.
He lost the back-and-forth fight via rear-naked choke submission late in the third round. Pettis faced Yaotzin Meza on June 7, 2014 at UFC Fight Night: Henderson versus Khabilov. Pettis faced Matt Hobar on December 6, 2014 at UFC 181.
The bout also earned Pettis his second Fight of the Night bonus award.
Pettis faced Ryan Benoit in a flyweight bout on March 14, 2015 at UFC 185. After winning the first round, Pettis was dropped by left hook and finished off with a flurry of ground and pound from Benoit in the second round.
Pettis faced Chris Cariaso on October 3, 2015 at UFC 192. Pettis is expected to face Chris Kelades on April 23, 2016 at UFC 197.
Mixed martial arts
Ultimate Fighting Championship
Fight of the Night (Two times) versus
Alex Caceres, Matt Hobar
Resurrection Fighting Alliance
RFA Flyweight Championship (One time, First)
North American Fighting Championship
NAFC Bantamweight Championship (One time, Current).