Background
Wong, Shan S. was born on May 10, 1945 in Mankassar, Indonesia. Son of Kay K. and Mon L. (Lee) Wong. came to the United States, 1967.
(Chemical cross-linking reagents have attained great pract...)
Chemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.
http://www.amazon.com/gp/product/0849358868/?tag=2022091-20
( Since the publication of the first edition of Chemistr...)
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivity and resolution have facilitated the analysis of cross-linked products. Updated to reflect the advances of the 21st century, this book offers: • An overview of the chemical principles underlying the processes of cross-linking and conjugation • A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers • Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules • Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations
http://www.amazon.com/gp/product/084937491X/?tag=2022091-20
Wong, Shan S. was born on May 10, 1945 in Mankassar, Indonesia. Son of Kay K. and Mon L. (Lee) Wong. came to the United States, 1967.
Bachelor of Science, Oregon State University, 1970; Doctor of Philosophy, Ohio State University, 1974.
Visiting assistant professor, Denison U., Granville, Ohio., 1977-1978; assistant professor, U. Lowell, Massachusetts, 1978-1982; associate professor, U. Lowell, Massachusetts, 1982-1984; professor of chemistry, U. Lowell, Massachusetts, 1984-1990; associate professor, University Texas Medical School, Houston, since 1990; section chief specimen collection, Reference Laboratory chief clinical chemistry, Hermann Hospital chief clinical chemistry, Lyndon B. Johnson General Hospital.
( Since the publication of the first edition of Chemistr...)
(Chemical cross-linking reagents have attained great pract...)
Member American Association Clinical Chemistry (travel award 1986), American Society Biochemistry and Molecular Biology, American Chemical Society, National Academy Clinical Biochemistry.
Married Lee-Jun Chang, February 21, 1973. Children: Inyork H., I. Hansie.