Career
O'Keefe competed on the now defunct PWBA Tour and was runner-up rookie of the year in that tour's final season (2003). She earned a spot on Team USA in her first attempt in 2005, and has been a member for the last Ten years. Other bowling highlights include a fifth place finish in the 2007 USBC Queens Tournament, and a runner-up finish in the 2007 U.S. Women's Open.
She bowled a 299 on television in the U.S. Open quarterfinals, and at the time tied a record for the most consecutive strikes in a row on television (18 over two games). She finished in 5th place in the 2011 U.S. Women's open, and in 3rd place at the 2012 U.S women's open. She was an exempt bowler in 2009 in the PBA Women's Series, which was sponsored by the United States Bowling Congress (USBC).
She made the quarterfinals of the 2009 PBA Women's World Championship, which was the first women's World Championship under PBA sanction. Shannon O'Keefe is currently the McKendree University Women's Bowling Head Coach and in her first year, led her team to an 11th place ranking in NTCA. Prior to her bowling success, O'Keefe was a first team all-American centerfielder, while attending Portland State University. She had a .411 batting average as a freshman, with 15 outfield assists.
As a 15-year-old, she was among the final 160 women competing for a spot on the 1996 Team USA Softball Team. She continues to represent Team USA in bowling, O'Keefe was part of Team USA in 2011—the team that went to the WTBA World Women's Championships in Hong Kong and took home gold for the United States in the team event for the first time since 1987. On May 14, 2014, she was sanctioned (via Public Warning) by the US ADA for use of banned substance, Clomiphene.
In the 2015 U.S. Women's Open, O'Keefe qualified as the #1 seed but had to settle for her second runner-up finish in this tournament, as she was defeated by Liz Johnson in the September 6 final, 190–189.