Career
Born in Homburg vor der Höhe, she was the third of fifteen children born from the second marriage of Philip Louis, Duke of Schleswig-Holstein-Sonderburg-Wiesenburg with Anna Margaret of Hesse-Homburg. From her fourteen full-siblings, only seven survive adulthood: Frederick, Charles Louis, Eleanor Margaret (by marriage Princess of Liechtenstein), William Christian, Sophie Magdalene (Abbess in Quedlinburg), Anna Fredericka Philippine (by marriage Duchess of Saxe-Zeitz-Pegau-Neustadt) and Johanna Magdalene Louise. In addition, she had two further older half-siblings from her father"s first marriage with Catharina of Waldeck-Wildungen, of whom only one survive: Dorothea Elisabeth (by her two marriages Countess of Sinzendorf, Rabutin and Marchioness de Fremonville).
They had no children.
Sophie Elisabeth died in Schleusingen aged 31. She was buried in the Hallenkrypta of the Dom Street.Peter und Paul, Zeitz.