Tucci was born in Peekskill, New York, and grew up in nearby Katonah, the son of Joan (née Tropiano), a secretary and writer, and Stanley Tucci, Sr., an art teacher at Horace Greeley High School in Chappaqua, New York. His parents, both of Italian descent, had roots in Calabria. He is the oldest of three children; his sister is actress Christine Tucci. Screenwriter Joseph Tropiano is a cousin. During the early 1970s, the family spent a year living in Florence, Italy.