Takatomi Senke was a leading figure in Shinto circles as the head priest of the Izumo Grand Shrine since 1872. He became the head of the Shinto Taishakyo a Shinto Sect in 1884. Later he was created a Baron.
Resigning as head of the sect (1888), he entered politics, was nominated a member of the House of Peers and appointed chief of the General Achool Affairs Bureau, Education Ministry, and governor of various prefectures. He was appointed Justice Minister in the Saionji Cabinet (1908). Well versed in Japanese classics, he was good also at composing waka.