Andhyarujina was a student of the Government Law College, Mumbai, between 1955 to 1957. He was awarded the Sir Charles Sergeant Scholarship and the Vishnu Dhurander Gold medal in law by the Bombay University. He was selected for the Indian Foreign Service in 1958 but opted to practise law.
He is a designated senior advocate and practises at the Supreme Court of India. He was the Solicitor General of India from 1996 to 1998. Prior to that he was the Advocate-General of Maharashtra from 1993 to 1995.
He specializes in the field of constitutional law, human rights, public law and commercial law.
He is widely regarded for his expertise in a branch of constitutional law relating to parliamentary privileges. Andhyarujina was a counsel in the chamber of H M Seervai, the then Advocate-General of erstwhile Bombay state from 1958 to 1974 and appeared for the State of Maharashtra in the Bombay High Court and the Supreme Court of India alongside him.
Before joining the Bar, Andhyarujina was selected as Indian Foreign Services in 1958. He secured 3rd rank in the ICSE (now UPSC) examination.
Some of the important cases in which he has appeared in the Supreme Court are: Kesavananda Bharati v.
Union of India, Glanrock Estate v. State of Tamil Nadu, Aruna Shanbaug v. Union of India (the recent case that permitted passive euthanasia in India), and Novartis v.
Union of India & Others (concerning evergreening of patents).
He was the Chairman of the Committee on Banking Laws (Andhyarujina Committee) appointed by the Government of India in 1998 which led to the passing of the Securitisation and Reconstruction of Financial Assets & Enforcement of Security Interest Acting, 2002 (SARFAESI Acting). He was a part-time Professor in Constitutional Law in the University of Bombay, a visiting Lecturer at Queen's University of Belfast in 1990 and an Honorary Professor at the National Law School of India University, Bangalore, Symbiosis Law School, Pune and other leading law colleges in India.
He is a member of the Task Force on the Committee on Centre–State Relations Review appointed by the Government of India in 2007.
