Education
He was educated at John Ruskin Grammar School, the University of East Anglia (Bachelor of Science) and the National Institute for Medical Research (Doctor of Philosophy).
He was educated at John Ruskin Grammar School, the University of East Anglia (Bachelor of Science) and the National Institute for Medical Research (Doctor of Philosophy).
He pioneered the method of cDNA cloning, an approach universally used in bioscience and biotechnology, and elucidated the organization, diversity and rearrangement of human antibody genes, which defined the building blocks for construction of therapeutic antibody repertoires. He also pioneered chimaeric antibodies (with Michael Neuberger). He discovered the LMO and HOX11 chromosomal translocation families in T cell leukaemia and the first fusion gene in a solid tumour.
He developed the first knock-in gene, now a widely employed approach in gene targeting and gene editing.
He was awarded the Colworth Medal in 1981, made a Fellow of the Royal Society in 1987.
Royal Society.