Her first television role was playing Anne Baxter in the soap opera Neighbours. She also played the lead role in the Australian short film, Hugo. James joined the cast of Home and Away as Nicole Franklin in 2008.
In an interview, James stated that she likes playing Nicole because they are complete opposites and that she is not a fan of wearing lots of make-up, unlike Nicole.
In March 2011, James confirmed that she had left Home and Away after three and a half years. She plans to audition for roles in Los Los Angeles