Bachelor in Biochemistry, Oxford (England) University, 1980; Doctor of Philosophy in Biochemistry, University of California, San Francisco, 1984.
Assistant professor University California, San Francisco, 1987-1992, associate professor, 1992—1997. Co-director Harvard Med School Institute Chemical and Cell Biology, Boston, 1997—2005. Professor cell biology Harvard Med School, 1997—2003, Hasib Sabbagh professor, since 1999, professor systems biology, since 2003.
Fellow American Academy Arts and Sciences, Royal Society. Member American Society Cell Biology.