In 1986 Okegwo moved to Berlin and studied with bassist Jay Oliver and pianist Walter Norris.
As a youngster he enjoyed working with his hands and played the electric bass. At age 21, he took a class in violin-making and started playing the upright bass. He then joined trombonist Lou Blackburn"s group for a tour in Europe and played with Joe Newman, Oliver Jackson and Major Holley.
In 1989 Okegwo moved to New York City and worked with saxophonists Big Nick Nicholas, Junior Cook and James Spaulding.
He worked with vocalist Jon Hendricks on a regular basis. He earned a Bachelor"s degree in Fine Arts from Long Island University, graduating summa cum laude in 1994.
In the early 1990s Okegwo formed a trio with pianist Jacky Terrasson and drummer Leon Parker. In 1997 he started to perform regularly in Tom Harrell ensembles.
In 2002, Okegwo released his first album as a leader titled Uoniverse.
About creating music, Okegwo stated that producing a note is human and personal and "in a rhythm section, the bass is the center, creating something constantly."
Okegwo has worked with a wide range of artists, including Kenny Barron, Michael Brecker, Benny Carter, Johnny Griffin, Wynton Marsalis, James Moody, Clark Terry, Pharoah Sanders, Steve Wilson, Michael Wolff, Bruce Barth, Steve Davis, Lionel Hampton, Sam Newsome, Kurt Rosenwinkel and others
He is a member of the Tom Harrell Quintet and the Mingus Big Band.