Born in Wollaton, Nottingham and educated at the Fernwood Comprehensive School, Vicky also attended the Central Television Workshop where she was spotted by Samantha Morton who helped launch her career.
She played the title character"s sister Ladine in A Room for Romeo Brass (1999), and featured in Meadows"s successful project and spin offs, This Is England (2006), This is England "86 (2010), This Is England "88 (2011) and This Is England "90 (2015). In an April 2007 interview with Time Out, McClure spoke of Meadows approaching her for the role while she was in a public with Andrew Shim. She described the making of the film, which was highly improvised, as "constant laughing and jokes."
She co-starred in the London-based comedy film Filth and Wisdom, the first feature film directed by popular singer Madonna.
She admitted to being slightly star-struck upon first meeting Madonna: "I tried to act as cool as possible but inside I"m like, “Oh my God.
There"s Madonna!” You can"t help lieutenant" The film premiered at the Berlin International Film Festival on 13 February 2008. She was also featured alongside Kaya Scodelario, Abbey Butler, Andy Crane and Paul Young in Plan B"s music video "She Said".
In 2010, Vicky appeared in a number of promotional short films for the English cosmetics brand Illamasqua. In 2013, she appeared in the British action-thriller film Hummingbird opposite Jason Statham.
McClure appeared in the video for Jake Bugg"s song "Two Fingers".
She will star as Winnie in the 2016 British Broadcasting Corporation drama The Secret Agent, based on the book of the same name by Joseph Conrad.