From 1864 to 1871, Leon attended gymnasium, then studied law in Berlin and later in Heidelberg, and graduated in Lviv in 1876.
After graduating, he spent one year serving in army. He did not apply for re-election in 1889. In 1908, he was again elected to the Diet of Galicia.
In 1910, he donated archives collected in Krasiczyn to Ossolineum.
He also contributed to running the Agricultural Academy in Dublany. Władysław Leon and Elżbieta Konstancja had ten children:
Kazimierz Leon Sapieha (1882–1906)
Józef Adam Sapieha (1887–1940)
Adam Zygmunt Sapieha
Andrzej Józef Sapieha (1894–1944)
Stanisław Sapieha (1896–1919)
Władysław Leon died on 29 April 1920 in Lviv and was buried in Krasiczyn.
He is great-great-grandfather of Queen Mathilde of the Belgians.
In 1883, he was elected deputy to the Diet of Galicia where he was member of the "Center" Parliamentary group along with Prince Jerzy Konstanty Czartoryski. As a deputy, he was a member of the parliamentary commissions of budget, mining, lustration and taxes. In 1883, he became a member of the Economic Society of Galicia.