Background
Weber, Wendell William was born on September 2, 1925 in Maplewood, Missouri, United States. Son of Theodore William and Flora Ann (Holt) Weber.
(Genes are important modifiers of human response to drugs,...)
Genes are important modifiers of human response to drugs, hormones, and toxins. Patients and healthy individuals alike display significant differences in response and suffer adverse effects as a result of exposure to many therapeutic agents as well as occupational chemicals. This introductory text brings together laboratory methods and epidemiological studies for defining the role of heredity in human drug response. The book is divided into two parts. Part I describes the emergence and broad scope of pharmacogenetics from an historical viewpoint, as well as the principles of pharmacology and genetics that are used to evaluate the importance and molecular genetic basis of pharmacologic/toxicologic mechanisms of hypersensitivity in humans and experimental animal models. Part II presents the experimental epidemiologic and clinical evidence for the genetics, molecular basis and clinical significance of thirty-three human traits of pharmacogenetic importance. The author includes an extensive discussion of the role of recombinant DNA technology Thus Part II illustrates the application of the basic principles discussed in Part I to real-life situations. This book will benefit upper-level graduate students in pharmacology, genetics, epidemiology, nursing, and public health, and will serve as a handy reference to pharmacists, epidemiologists, and physicians responsible for the delivery and administration of drugs.
http://www.amazon.com/gp/product/0195068785/?tag=2022091-20
Weber, Wendell William was born on September 2, 1925 in Maplewood, Missouri, United States. Son of Theodore William and Flora Ann (Holt) Weber.
AB, Central College, 1945; Doctor of Philosophy in Physical Chemistry, Northwestern University, 1950; Doctor of Medicine, University of Chicago, 1959.
Assistant professor of chemistry, U. Tennessee, Knoxville, 1949-1951; member operations research staff, United States Army Chemical Center, Edgewood, Maryland., 1951-1955; successively instructor, assistant professor, associate professor, professor pharmacology, New York University School Medicine, New York City, 1963-1974; professor, University of Michigan, Ann Arbor, 1974-1998; Distinguished lectureship in Biomedical Research, University of Michigan, 1993; emeritus professor, University of Michigan, since 1998; Distinguished lectureship Center for Environmental Genetics, U. Cincinnati, 1997. Member pharmacology-toxicology committee National Institutes of Health, 1969-1973, review committees, since 1968.
(Genes are important modifiers of human response to drugs,...)
Fellow New York Academy Sciences. Member American Society Pharmacology and Therapeutics, American Chemical Society, American Society Human Genetics, Society Toxicology (honorary), American Association for the Advancement of Science, Sigma Xi, Phi Lambda Upsilon.
Married La Donna Tavis, Sept.29, 1952. Children— Jane Holt, Theodore Wendell.