After graduating from Murray State University in 1986, Brown moved to Chicago where he received his Master of Fine Arts from DePaul University Theatre School in 1989.
He is perhaps best known for his role as Dan Dority on the Home Box Office series Deadwood. He also played Kenny in the 1996 film Scream and Warren in the 1998 film There"s Something About Mary. More recently, he voiced and filmed performance capture for the character Bill in Naughty Dog"s 2013 survival horror action video game The Last of Us, and appeared in the series American Crime and the Johnny Depp true-crime film Black Mass (2015).
After performing in numerous plays, including his breakout performance in Steppenwolf Theatre Company"s outreach staging of Arthur Miller"s A View from the Bridge, Brown began work in television and film.
In 1993, Brown moved to Los Los Angeles He auditioned for, and was cast in Wes Craven"s New Nightmare.
He also has a minor role in Craven"s Vampire in Brooklyn, and a bigger one as Gail"s cameraman in Craven"s Scream. Two years later, Brown played the role of Warren in the comedy film There"s Something About Mary.
Other past films credits include Being John Malkovich, Vanilla Sky, Dancing at the Blue Iguana, The Alamo, and The Big White.
In 2009, Brown wrote and produced the Samuel Goldwyn Company/Sony release Bloodworth. Among Brown"s more recent film credits are the Oscar-nominated films The Master and The Sessions and 2013"s The Lone Ranger and Brother"s Keeper, and 2014"s Wild. On television, Brown is best known for his portrayal of Dan Dority in Home Box Office"s Deadwood.
During the show"s second season, he was invited to join the show"s writing staff by its creator, David Milch.
In 2007, Brown earned a WGA nomination for writing on a drama series and a Screen Actors Guild nomination for best drama ensemble acting. Over the years, his numerous guest star roles on television include: Bates Motel, Rectify, Luck, American Horror Story, Justified, Six Feet Under, New York City Police Department Blue, X-Files, The Mentalist, Computer Society of India: Crime Scene Investigation, Ellen, Seinfeld, True Detective, and others
Among the many television movies he has been involved with was the starring role in Video Hits One"s Meatloaf: To Hell and Back. In addition to his television and film work, Brown performed the motion capture and voiceover work for Naughty Dog"s acclaimed video game, The Last of United States
He also writes and records with the Los Angeles band Sacred Cowboys, who performed around the Southwest United States. steadily from 2005 to 2009, including having been on the bill for Stagecoach 2009, Southern California"s premiere country music festival.