Career
Initially there were a group of paintings attributed to an anonymous painter referred to as the "Master of Santo Spirito". They worked together in a workshop in Florence during the late fifteenth and early sixteenth centuries. There is some difficulty in precise attribution due to the collaborative nature of the brothers, but paintings originally assigned to "Master of Santo Spirito" have been variously attributed to Agnola or to both.
According to tax documents Donnino was the head of the workshop, which began sometime after 1480.
Their style suggests that they may have apprenticed with Cosimo Rosselli. Agnola"s mention in Giorgio Vasari"s Lives of the Most Excellent Painters, Sculptors, and Architects as well as by Filippo Baldinucci, indicates that he was the more recognized and talented of the brothers.
Agnolo was among a group of select artists to consult with Michelangelo for the Sistine Chapel ceiling between 1507 and 1508. One painting of the Mazziere studio was an altarpiece for the hospital church of Santa Lucia in Florence in 1490.