Background
Wolffe, Alan Paul was born on June 21, 1959 in Burton-on-Trent, Staffordshire, England. Son of Ronald and Mildred (Hasbury) Wolffe.
( The Third Edition of Chromatin: Structure and Function ...)
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active involvement in the processes of DNA transcription, replication and repair. This book consistently interrelates the structure of eukaryotic DNA with the nuclear processes it undergoes, and will be essential reading for students and molecular biologists who want to really understand how DNA works. • Written in a clear and concise fashion • Includes 60 new illustrations • Extensively rewritten • Brings the reader up-to-date with the remarkable progress in chromatin research over the past three years.
http://www.amazon.com/gp/product/0127619151/?tag=2022091-20
molecular embryologist molecular biologist
Wolffe, Alan Paul was born on June 21, 1959 in Burton-on-Trent, Staffordshire, England. Son of Ronald and Mildred (Hasbury) Wolffe.
Bachelor with honors in Biochemistry, University of Oxford, 1981; Doctor of Philosophy, Medical Research Council London, 1984.
He was successful at biology early on, receiving the Biological Council Prize upon leaving secondary school. He did his Doctor of Philosophy under Professor Jamshed Tata at the National Institute for Medical Research, London.
He was awarded an European Molecular Biology Organization long-term postdoctoral fellowship in 1984 and moved to the laboratory of Donald Doctorate. Brown at the Department of Embryology, Carnegie Institution of Washington in Baltimore.
He joined the National Institute of Health in 1987, working firstly with Gary Felsenfeld in the Laboratory of Molecular Biology (National Institute of Arthritis, Diabetes and Metabolic Diseases). In 1990 he was appointed Chief of the newly founded Laboratory of Molecular Embryology (LME).
He left National Institutes of Health and moved to the biotechnology firm Sangamo BioSciences Incorporated. in Richmond, California in 2000, as Senior Vice President and Chief Scientific Office. He was a prolific writer, publishing hundreds of articles, literature reviews and two books
He will be known mainly for his work in promoting the idea that chromatin plays a dynamic role in regulating gene expression.
He died as a result of injuries suffered in a road accident in Rio de Janeiro on May 26, 2001.
( The Third Edition of Chromatin: Structure and Function ...)
Member American Association for the Advancement of Science, American Association Cancer Research, American Society Microbiology, American Society Cell Biology, British Society Development Biology, Biochemical Society (United Kingdom).
Married Elizabeth Jane Hall, August 21, 1982.