Career
Reputed one of the handsomest men of his day, Lowther was first returned to Parliament for Cockermouth in 1721 in a by-election upon the death of Lord Percy Seymour. This was arranged on the interest of the Lawsons of Isell. At the 1722 election, Sir Wilfrid Lawson took the Cockermouth seat himself, while Lowther was returned through his own family"s interest for Westmorland.
In 1726 he obtained a position as commissioner of the revenue for Ireland, which he resigned in 1734, apparently out of pique at not receiving any greater preferment.
Lowther opposed the Convention of Pardo in 1739. He did not stand in the 1741 election in May and died that November, unmarried.