Bachelor of Science, Carnegie-Mellon University, 1968. Doctor of Science in Microbiology, University Pittsburgh, 1972.
Research assistant University Pittsburgh, 1971—1972, assistant research professor, 1972—1974. Principal scientist Meloy Laboratories, Inc., Springfield, Virginia, 1974—1978, managing director, 1979—1980. Technical director biological products Flow Laboratories, Inc., McLean, 1980—1982.
Manager cell culture operations Genentech Inc., South San Francisco, 1982—1983, director cell culture Research and Development, 1983—1988. Vice president biopharmaceutical manufacturing and development Smith Kline & French Laboratories, King of Prussia, Pennsylvania, 1988—1989. Vice president, director biopharmaceutical development SmithKline Beecham Beechum, 1989—2000.
Vice president biopharmaceutical development GlaxoSmithKline, since 2000. Member material technical advisory committee Material Technology Advisory Committee, Department Commerce, 1997. Adjunct professor chemical and biochemical engineering University Maryland, Baltimore County, since 1991.
Chairman biotechnology process validation committee United States Pharmacopeia, 1999—2000. Member advisory committee on xenotransplantation Secretary of Department of Health and Human Services, since 2001.
Member American Association for the Advancement of Science, American Society Microbiology, Pharmaceutical Manufacturers Association (vice-chairman biological and biotechnology section, chairman process technical committee, biotechnological advising committee), International Association Biological Standardization (editor Biologicals), New York Academy Sciences, European Society Animal Cell Technology (Hy Clone award for Outstanding Contributions to Animal Cell Biotechnology 1991), Society Experimental Biology and Medicine, Parenteral Drug Association.
Married Robin Lea Brudowsky, June 8, 1968. 1 child, Gregory.