Background
Childs, Barton was born on February 29, 1916 in Chicago, Illinois, United States. Son of Robert William and Katherine Sayles (Barton) Childs.
Childs, Barton was born on February 29, 1916 in Chicago, Illinois, United States. Son of Robert William and Katherine Sayles (Barton) Childs.
Childs studied the genetics of adrenal hyperplasia, Crigler-Najjar syndrome, and propionic acidemia.
In 1942, he received his Doctor of Medicine from Johns Hopkins University. Following military service in World World War II, he returned to Johns Hopkins for a residency in pediatrics. After a fellowship at Children’s Hospital in Boston, he returned to Johns Hopkins University in 1949, where he remained until his retirement in 1981.
He remained a professor emeritus in the Department of Pediatrics at The Johns Hopkins University School of Medicine until his death.
He is known for his collaboration with William H. Zinkham, which demonstrated that Glucose-6-phosphate dehydrogenase deficiency is an X-linked recessive genetic disease. He is best known for a collaboration with Ronald Davidson and Harold Nitowsky, which demonstrated random inactivation of one of the two X-chromosomes in mammalian female cells, a mechanism of dosage compensation.
Childs was the author of many editorial pieces on genetic counseling, genetic screening, and behavioral genetics. He was a coauthor of The Metabolic and Molecular Bases of Inherited Disease, published in four volumes.
In his book Genetic Medicine: A Logic of Disease, published in 1999, he argues that in the future, all medicine, or medical theory, must be based on the individuality of gene-environment interaction.
Served to captain, Medical Corps Army of the United States, 1943-1946. Member American Pediatric Society, Society Pediatric Research, American Academy Pediatrics, American Society Human Genetics, Genetics Society American, Institute Medicine, American Academy Arts and Sciences.
Married Eloise L.B. MacKie, March 29, 1950 (deceased 1980). Children: Anne Lloyd, Lucy Barton. Married Ann E. Pulver, December 1986.