Background
Carl was born on March 7, 1885 in Brown County, South Dakota, United States, the son of Gustav Schmidt and Fridericke (Unverzagt) Schmidt.
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Carl was born on March 7, 1885 in Brown County, South Dakota, United States, the son of Gustav Schmidt and Fridericke (Unverzagt) Schmidt.
Schmidt received his early education in local schools and entered the University of California, Berkeley, earning the B. S. degree(Bachelor of Science) in 1908, the M. S. (Master of Science) in 1910, and the Ph. D. (doctor of philosophy) in 1916.
From 1908-1909 Schmidt was employed as a chemist by the Metropolitan Light and Power Company in San Francisco and later by the Referee Board of the U. S. Department of Agriculture (1909 - 1912). From 1912-1914 he worked for the city of Berkeley as a bacteriologist and chemist.
In 1915 Schmidt returned to the University of California as research assistant in physiology, achieving the rank of professor of biochemistry in 1924. His leadership in biochemistry at the Berkeley campus served to promote the educational and research facilities in the medical school as well as in biochemistry itself.
His long-term interest in proteins and amino acids resulted in a definitive article, "The History of the Discovery of the Amino Acids, " written with Hubert B. Vickery and published in 1931 in Chemical Review. His more than 150 papers reflect the areas of his greatest interest: the biochemistry of bile, especially with respect to its function in the absorption of fat-soluble vitamins and the consequent relationship of this property to the bleeding tendency in obstructive jaundice.
Schmidt's researches in the physical chemistry of proteins and amino acids provided some of the most fundamental aspects of current knowledge in the medical regions or areas of these substances. He investigated the antigenic properties of hemoglobin and hemocyanin, finding them to be negative and positive, respectively. He also conducted immunological experiments with enzymes such as catalese and with denatured and insoluble proteins. He studied red cell globulins and discerned the fact that injections of pure proteins had no noticeable effect upon the production of serum albumin or globulin (in rabbits). But his condition to immunology lies principally in his ability to transfer biochemical data into forms suitable to the practice of medicine.
From 1937-1944 Schmidt served as dean of the college of pharmacy at the university; he was also acting dean of the medical school from 1938-1939.
His publications include The Chemistry of the Amino Acids and Proteins (1938) and, with Frank W. Allen, Fundamentals of Biochemistry (1938).
Schmidt died in Berkeley of carcinoma; his remains were cremated.
(Unlike some other reproductions of classic texts (1) We h...)
Schmidt was a meticulous worker, a good organizer, and a competent administrator.
On 11 April 1914 Schmidt married Esther May Skolfield, a graduate of and bacteriologist at the State Board of Health in Berkeley. For a number of years they worked and published jointly on problems of bacteriology and immunology.