Education
Master of Science in Biology, University Utrecht, Netherlands, 1979. Doctor of Philosophy, University Amsterdam, 1982.
Master of Science in Biology, University Utrecht, Netherlands, 1979. Doctor of Philosophy, University Amsterdam, 1982.
Research fellow Netherlands Cancer Institute, Amsterdam, 1982—1988, senior science staff member, 1988—1994. Professor cell biophysics University Twente, Enschede, Netherlands, 1992—2009. Professor experimental tumor immunology, head department tumor immunology Radboud University Nijmegen Medical Center, Netherlands, since 1994, co-director, Nijmegen Center Molecular Life Sciences, 2001—2003, science director, Nijmegen Center Molecular Life Sciences, since 2004.
Achievements include patents for antigen uptake receptor for candida albicans on dendritic cells. Patents for District of Columbia-SIGN by macrophages and methods of treating and diagnosting rheumatoid arthritis. Patents for composition and method for modulating dendritic cell-T cell interaction.
Patents for melanoma associated antigenic polypeptide, epitopes thereof and vaccines against melanoma. Patents for cell-separation. Patents for method and device for the separation and isolation of blood or bone marrow components.
Patents for apparatus for liquid separation. Patents for method for modulating the binding activity of a novel ICAM-3 binding receptor on sinusoidal endothelial cells in liver and lymph nodes.
Member of Netherlands Cancer Institute (science advisory board member), Royal Dutch Academy of Sciences (biochemistry and biophysics board committee), Science Committee Catholic University Nijmegen, VICI Committee Dutch Science Organization (New World Order), Dutch Society Immunology (board member, Van Loghum award 1999), Dutch Cancer Society (science board member, Research grant 2008-2009, Koningin Wilhelmina prize 2009), Belgian Organization Funding Science Research (science committee member).
Married.