Background
Cheng, Chuen Yan was born on June 18, 1954 in Hong Kong. Came to the United States, 1981, naturalized, 1993. Son of C. Yin and Tak Ying (Ho) Cheng.
Cheng, Chuen Yan was born on June 18, 1954 in Hong Kong. Came to the United States, 1981, naturalized, 1993. Son of C. Yin and Tak Ying (Ho) Cheng.
Bachelor of Science with honors, Chinese University, Hong Kong, 1978. Doctor of Philosophy, University Newcastle, Australia, 1982.
Since the population of undifferentiated spermatogonia and spermatogonial stem cells in the testis following adjudin treatment is not affected, the adjudin-induced infertility is transient and its anti-fertility effect is reversible. Recently finished animal studies showing no side-effects. However, the margin between its efficacy and toxicity following 29-day use in laboratory rats based on a subchronic toxicity test is narrow.
Subsequent studies in the laboratory have shown that an endogenously produced biologically active peptide in the testis known as F5-peptide can effectively and transiently break-down the blood-testis barrier.
These findings thus illustrate that this F5-peptide can be used in conjunction with adjudin in a multi-drug approach for male contraception. Recent studies have demonstrated other potential health benefits of adjudin including its anticancer anti-inflammatory and anti-ototoxicity activity, illustrating its potential health benefits following long-term use at low doses.
Adjudin.
Member American Society Andrology (Best Science Paper award 1996), Endocrine Society (Richard E. Weitzman Memorial award 1988).
Married Po Lee, March 17, 1978. Children; Yan Ho, Chin House.