Education
He trained in theoretical population genetics at Stanford University (Doctor of Philosophy 1994), where he worked with Marcus Feldman and Luca Cavalli Sforza.
He trained in theoretical population genetics at Stanford University (Doctor of Philosophy 1994), where he worked with Marcus Feldman and Luca Cavalli Sforza.
Goldstein is founding Director of the Institute for Genomic Medicine at the Columbia University Medical Center, Professor of Genetics and Development and directs the genomics core of Epi4K and administrative cores of Epi4K with Dan Lowenstein and Sam Berkovic. Goldstein"s primary research interests include human genetic diversity, the genetics of disease, and pharmacogenetics. The Goldstein group and collaborators have discovered a number of disease causing genes and syndromes, in particular in neurological and infectious diseases including: The role of IL28B in response to treatment for Hepatitis C infection in collaboration with John McHutchison and others
Identification of ATP1A3 as the gene responsible for Alternating Hemiplegia of Childhood in collaboration with Erin Heinzen and others
Discovery of NGLY1 deficiency as a new syndrome in collaboration with Vandana Shashi, Anna Need, and others New genes for epileptic encephalopathies as part of the Epi4K Consortium.
1996-1999: Lecturer, University of Oxford 1999-2005: Wolfson Professor of Genetics, University College London 2005–2014: Richard and Pat Johnson Distinguished University Professor of Genetics, Microbiology, and Biology, Duke University and Director for the Center for Human Genome Variation 2014-present: John East. Borne Professor of Medical and Surgical, Columbia University and Director, Institute for Genomic Medicine, Columbia University Medical Center.
Goldstein was elected a fellow of American Association for the Advancement of Science in 2013, received the University of North Carolina at Chapel Hill IPIT award for clinical services in 2012, and was a recipient of one of the first seven nationally awarded Royal Society / Wolfson research merit awards in the United Kingdom for his work in human population genetics. In 2013, Goldstein chaired the Gordon Conference in Human Genetics, and he is currently serving on the Advisory Council at the National Institute of Neurological Disorders and Stroke at National Institutes of Health.
