Grisard studied at Federal University of Santa Catarina from 1985 to 1991 and earned his Bachelor of Science in biological sciences. Eight years later he received a Doctor of Philosophy degree in parasitology from Federal University of Minas Gerais. Also he attended the University of California in Los Angeles from 1997 to 1998.
Grisard began his career as a professor of the Microbiology, Immunology and Parasitology Departmentat at Federal University of Santa Catarina in 1994 and held it to the present. In 2001, he became a research fellow at National Council for Scientific and Technological Department. In 2007, Edmundo held the position of a visiting scientist at the University of East Anglia, where he worked until 2008.
Edmundo Grisard is married to Fabiane Borges da Silva Grisard. They have a child.