Lyford attended the Coburn Classical Institute and Colby University, from which he graduated with an Bachelor of Arts degree in 1877, and a Master of Arts in 1882.
Reuben Foster. Lyford also worked as a teacher while he lived in Waterville, teaching in the local schools and at Colby University. Lyford was admitted to the Maine Bar in 1879.
In 1882 Lyford moved to Springfield and was admitted to the Massachusetts Bar in that year.
Massachusetts House of Representatives
In 1892-1893 Lyford represented the Seventh Hampden District in the Massachusetts House of Representatives. In the House of 1892 Lyford was the Clerk of Committee on Cities and the Chairman of House Committee on Probate and Insolvency.
Lyford was also on the Committee on Constitutional Amendments in the House of 1893. Lyford was the Chairman of Special Committee to investigate the Bay State Gas Company.
In 1894 Lyford served in the Massachusetts State Senate representing the First Hampden District.
While in the Senate, Lyford was the Chairman of committee on probate and insolvency, and on the committees on judiciary and taxation, and special committee on revision of corporation laws, also chairman of the special committee on the unemployed, 1894.
Lyford was a member of the for two years in 1885 and 1886.