She is known for the 2010 play Oliver Parker!, the 2011 romantic comedy film Number Strings Attached, and the sitcom New Girl for Fox, starring Zooey Deschanel. Her family moved from Miami, Florida, to Detroit, Michigan when she was five years old, and then to Ann Arbor, Michigan, when she was 10. Her father, Heath J. Meriwether, was the publisher of the newspaper Detroit Free Press, and her mother was a painter.
Meriwether grew up aspiring to be an actor, but when she wrote her first play, she realized she wanted to be a playwright instead.
Meriwether went to Greenhills High School in Ann Arbor, and then attended and graduated from Yale University. Meriwether wrote the plays Heddatron (2006), The Mistakes Madeline Made (2006), and Oliver Parker! (2010).
She also wrote the screenplay for the 2011 romantic comedy film Number Strings Attached. She has also written for the Adult Swim television series Childrens Hospital, is working with Fox Broadcasting Company as the creator of New Girl, and is developing projects for studios Universal and Paramount.
Meriwether is part of "The Fempire", a group of female screenwriters that include Dana Fox, Diablo Cody and Lorene Scafaria.
She is also a well-known feminist, who has done stand-up comedy, and performed for the Vagina Monologues in Las Vegas.