Everly Conway de Macario

Background

Macario, Everly Conway de Daughter of Delfin E. and Maria Gloria (Benatuil) Conway.

Education

Doctor of Philosophy in Pharmacy, National University Buenos Aires, 1960. Doctor of Philosophy in Biochemistry, National University Buenos Aires, 1962.

Career

Research fellow National Academy Medicine Argentina, Buenos Aires, 1962-1963. Head laboratory oncology and immunology Argentinian Association against Cancer, 1966-1967. Chief of immunology School Medicine, 1967-1968.

Research fellow department tumor-biology Karolinska Institute, Stockholm, 1969-1971. Senior research scientist Laboratory Cell Biology, National Research Council Italy, Rome, 1971-1973. Visiting scientist International Agency Research on Cancer, World Health Organization, Lyon, France, 1973-1974, Brown University, Providence, 1974-1976.

Research scientist Wadsworth Center New York State Department Health, Albany, 1976—2006. Professor department biomedical science School Public Health, 1986—2002, member admission committee, 1986-1989. Scientist University Maryland Biotechnology Institute, 2004—2010.

Adjunct professor Department Microbiol. and Immunology, School Medicine, University Maryland, Baltimore, since 2010. Grant referee in field.

Achievements

• Achievements include patents for micro circle system, micro sample holder and carrier. Invention of ultra sensitive micro-immunoenzyamtic assay and multipurpose modular system. Discovery of oscillations of antibody affinity during maturation of the immune response, diversity of methanogens in natural and manufactured ecosystems.
  
  Development of antibodies and immunochemical methods for dissecting the antigenic mosaic of archaeal organisms and determination of the identity of methanogens as a distinct and antigenically coherent group of prokaryotes different from bacteria. First to identification of the predominant archaeal organism in the human colon, periodontal space, and vagina, and ascertainment that it is Methanobrevibacter smithii. Elucidation of population dynamics of defined methanogenic species in microbial consortia.
  
  Discovery of the structural topography of methanogens in microbial consortia. Isolation for the first time of the ABC-transporter genes and the genes in the hsp70/dnaK locus from an archaebacterim (archaeon). Discovery of determination that the archaeal hsp70 genes belong to various evolutionary lineages.
  
  Discovery of a unicelled organism with the main four chaperoning system in the cytoplasm. Identification of two new chaperonins in archaea. Development of first integration vector for genetically engineering a methanogen useful for waste bioconversion.
  
  Development of the concept of sick chaperone or chaperonopathy as a factor contributing to the ageing process and disease. Elucidation of the entire set of hsp70 genes in the human genome. Characterization of the whole complement of cct-Hsp60 genes in the human genome.

Works

More photos

• book

  • Monoclonal Antibodies Against Bacteria
  • Monoclonal Antibodies Against Bacteria, Vol. 2
  • Monoclonal Antibodies Against Bacteria, Vol. 3
  • Monoclonal Antibodies Against Bacteria
  • Monoclonal Antibodies against Bacteria. Volume III.

• Other Work

  • Editor: Monoclonal Antibodies against Bacteria, 1985-1986, vols. I-III, Gene Probes for Bacteria, 1990. Associate editor professional journal since 1986.
    
    Managing editor Frontiers on Bioscience. Contributor articles to professional journals. Contributor chapters to books and encyclopedias.

Membership

Past member Scandinavian Society Immunology, Italian Association Immunologists, French Society Immunology. Member American Association Immunologists (chairman committee on status of women 1980-1986, education committee 1982-1987, awards committee 1991-1992, travel award to Australia 1977), American Society Microbiology (senior editor Manual Clinical Laboratory Immunology 4th-5th editions), International Society Microbial Ecology, Cell Stress Society International, National Academy Microbiology (chairman Morrison Rogosa awards committee 2002-2006, chairman international subcommittee on taxonomy of methanogens).

Connections

Married Alberto J. L. Macario, March 16, 1963. Children: Alex, Everly.

Father:

Delfin E. Conway

Mother:

Maria Gloria (Benatuil) Conway

Spouse:

Alberto J. L. Macario

child:

Alex Macario

child:

Everly Macario