Doctor of Medicine, Berlin University, 1960. Doctor of Philosophy, Academy of Sciences Germany, Berlin, 1978.
Assistant physician City Hospital, Fürstenberg, Germany, 1960-1961, German Academy of Sciences, Berlin, 1961—1992. Scientist Institute Molecular Biology, 1962-1969, group leader, 1969-1980, head department, 1981-1991. Professor immunology German Academy of Sciences, 1988.
Science director Institute Medical Diagnostics, 1992—2000, Institute Laboratory Medicine, Berlin, 2001—2006. Board directors Diagenics, Dusseldorf, Germany, since 2001, International Corporation, Woburn, Massachusetts. Lecturer Humboldt University, Berlin, 1976-1995, Free University Berlin, 1991—2002.
Member of New York Academy of Sciences, German Association for Laboratory Medicine, German Association for Immunology.
Married Waltraut Negelein, September 30, 1936. Children: Thomas, Claudia.